rat spleen tissue were subjected to SDS PAGE followed by western blot with FNab02102( CXCR4 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab02102(CXCR4 antibody) at dilution of 1:100
Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.